As seasoned optometrists, we frequently receive inquiries regarding whether nutritional supplements can truly enhance eye health or alleviate chronic symptoms. In many instances of eye-related issues, optimal nutrition plays a crucial supportive role. One area with compelling research backing is dry eye disease, where both nutrition and targeted supplementation can yield significant improvements.

Numerous clinical studies consistently demonstrate that a well-balanced diet, when coupled with specific supplements, can enhance tear quality, diminish inflammation, and foster long-term ocular comfort. This compelling body of evidence underscores the importance of incorporating supplements into a comprehensive management plan for effectively addressing dry eye symptoms.
Two well-known supplements that are often discussed in this context are Lacritec and DRYeye Forte. While both products aim to soothe dry eye symptoms, they differ markedly in their formulations, strength, and the effectiveness of their ingredients within the body.
This thorough comparative analysis elucidates these differences, empowering you to make an informed decision regarding your approach to managing dry eye symptoms.
Detailed Ingredient Analysis for Lacritec and DRYeye Forte
Key Ingredients Present in DRYeye Forte
- 667 mg of re‑esterified omega‑3 triglycerides per capsule
- 240 mg of EPA
- 160 mg of DHA
- 455 mg of borage oil providing 100 mg of GLA
- 200 IU of Vitamin D3
- 40 IU of natural Vitamin E
Primary Ingredients in Lacritec
- 332 mg of omega‑3 triglycerides per capsule
- 134 mg of EPA
- 66.8 mg of DHA
- 334 mg of flaxseed oil
- Provides 192 mg of ALA
- 434 mg of borage oil supplying 95.5 mg of GLA
- Absence of Vitamin D3
- Absence of Vitamin E


Understanding the Importance of Different Omega‑3 Fatty Acids
While both supplements contain omega‑3 fatty acids, it is vital to comprehend that not all omega‑3s function in the same way within the human body.
Lacritec includes flaxseed oil, which is a source of ALA. Although ALA is recognised as an omega‑3 fatty acid, the human body can only convert a limited percentage of ALA into the more crucial forms responsible for alleviating dry eye symptoms, namely EPA and DHA. Research indicates that the conversion rates of ALA to EPA are approximately 8–12 percent, with the majority of ALA being used as an energy source rather than for supporting eye health.
Conversely, DRYeye Forte offers EPA and DHA directly, using higher concentrations in a re‑esterified format. This advanced manufacturing technique improves both absorption and bioavailability, ensuring that a larger proportion of the active ingredients effectively reaches the tissues where they are most needed.
When assessing the effective levels of EPA and DHA:
- Three capsules of DRYeye Forte deliver a significantly greater amount of EPA and DHA compared to three capsules of Lacritec.
- To achieve the same EPA and DHA content found in three capsules of DRYeye Forte, you would need to consume approximately six Lacritec capsules.
Both supplements recommend beginning with three capsules daily during the treatment stage, making this difference clinically significant for users seeking effective relief.


Assessing the Quality and Sourcing of Fish Oil in Supplements
Both Lacritec and DRYeye Forte are produced in Australia, utilising high-quality fish oils sourced from small, cold-water fish such as sardines and anchovies harvested from Peru. Smaller fish are known to accumulate fewer toxins, making them a safer option for supplementation. Both oils undergo stringent purification and deodorisation processes to eliminate impurities and minimise any undesirable fishy aftertaste.
DRYeye Forte incorporates re‑esterified triglyceride fish oil, which has demonstrated superior absorption compared to traditional ethyl ester forms. This innovative approach not only enhances consistency but also lessens gastrointestinal discomfort for many users, making it a preferred choice for those seeking effective supplement options.
Unpacking the Role of Vitamin D and Vitamin E in Supporting Eye Health
A significant distinction between the two supplements is that DRYeye Forte contains both vitamin D3 and natural vitamin E in its formulation, both of which can substantially impact eye health.
The Benefits of Vitamin D3 for Eye Health
Research has identified a strong link between low levels of vitamin D and symptoms of dry eye. Studies indicate that vitamin D may:
- Mitigate ocular inflammation
- Enhance tear stability
- Promote healing of the ocular surface
- Alleviate light sensitivity and general ocular discomfort
The Multiple Advantages of Vitamin E
Vitamin E plays an essential dual role. It offers both antioxidant and anti-inflammatory properties while also protecting omega‑3 fatty acids from oxidative damage. Long-term fish oil supplementation can increase the body's requirement for vitamin E, making its inclusion vital for maintaining balance and optimising omega‑3 metabolism.
In contrast, Lacritec does not contain either vitamin D3 or vitamin E, which may limit its overall effectiveness in promoting eye health.
Assessing the Safety and Tolerability of Eye Health Supplements
Both supplements are generally well tolerated when taken according to the suggested dosage guidelines.
Potential side effects from either product may include mild gastrointestinal disturbances such as reflux, bloating, or loose stools. These effects are usually dose-dependent and can differ from person to person.
Individuals on blood-thinning medications or those with bleeding disorders should seek advice from a healthcare professional before commencing either supplement.
Given the presence of vitamin D3 in DRYeye Forte, individuals with hypercalcemia, kidney conditions, or other conditions sensitive to vitamin D should consult with a healthcare professional prior to use. In these instances, Lacritec may be a more suitable option due to its absence of vitamin D.
As with all supplements, it is advisable to consult a healthcare provider if you are pregnant, breastfeeding, or managing chronic health issues.
Selecting the Optimal Supplement for Your Unique Needs
For the majority of individuals suffering from moderate to severe dry eye disease, DRYeye Forte offers more comprehensive and targeted support. This is attributed to:
- Elevated concentrations of effective EPA and DHA
- Enhanced absorption due to the use of re‑esterified fish oil
- The inclusion of vitamin D3 and vitamin E, which aid in controlling inflammation and supporting tear production
Lacritec may still be suitable for individuals with very mild symptoms or those who are unable to tolerate vitamin D supplementation.

Key Insights and Recommendations for Effective Dry Eye Management
Both supplements can positively contribute to alleviating dry eye symptoms; however, they are not interchangeable.
DRYeye Forte provides higher therapeutic doses of the most effective omega‑3 fatty acids, along with additional nutrients that help manage inflammation, enhance tear quality, and promote ocular surface health. For many patients, this results in more effective symptom relief with a reduced number of capsules required on a daily basis.
Ultimately, the most suitable supplement is one that seamlessly integrates into a personalised dry eye treatment plan. If you are uncertain about which product is best for your needs, we recommend consulting with your optometrist or healthcare provider for tailored advice.
Lacritec vs DRYeye Forte Frequently Asked Questions
Which supplement is more effective for dry eye relief: Lacritec or DRYeye Forte?
For the majority of individuals experiencing moderate to severe dry eye symptoms, DRYeye Forte emerges as the more effective option. It features higher levels of EPA and DHA, the active omega-3s recognised for their ability to reduce inflammation and enhance tear quality, supplemented by vitamin D3 and vitamin E for additional support. Lacritec may still provide benefits in milder cases or when vitamin D supplementation is not advisable.
What are the fundamental differences between Lacritec and DRYeye Forte?
The primary distinction lies in their formulations and potency. DRYeye Forte employs highly bioavailable re-esterified fish oils that deliver clinically significant doses of EPA and DHA, complemented by vitamin D3 and natural vitamin E. In contrast, Lacritec uses flaxseed oil, which provides ALA — an omega-3 source that is less efficient and has limited conversion into EPA and DHA.
How many Lacritec capsules are necessary to match the EPA/DHA dosage in DRYeye Forte?
To obtain equivalent levels of EPA and DHA found in three capsules of DRYeye Forte, you would need to ingest approximately six Lacritec capsules. This discrepancy arises from Lacritec's lower omega-3 concentration and its dependence on ALA, which only partially converts into the more bioactive forms that the body requires.
Is it safe to use DRYeye Forte if I have kidney issues or elevated calcium levels?
If you have kidney disease or hypercalcemia, it is crucial to consult your healthcare provider before starting DRYeye Forte. The inclusion of vitamin D3 may not be appropriate for individuals with these conditions. In such cases, Lacritec, which lacks vitamin D, may be a more suitable alternative.
Will I need to continue taking dry eye supplements indefinitely?
Not necessarily. Many individuals initiate treatment with a higher dosage (three capsules daily) for 6–8 weeks and then reassess their condition with their optometrist. Some may shift to a maintenance dosage or stop use altogether if their symptoms improve. However, ongoing supplementation may be beneficial for chronic or seasonal dry eye, particularly if there are underlying issues such as inflammation or oil gland dysfunction.
Lacritec vs DRYeye Forte: Which Supplement Is the Better Choice for Dry Eye Relief?
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